With approaches such as zinc finger nucleases, stem cells, and transposon mutagenesis, rats are becoming more popular as lab animals, reports The Boston Globe. Mice have long been the experimental animal of choice, but there are some instances in which mice are not as good a model for human systems. The Globe notes that the Michael J. Fox Foundation has been pushing for rat models of Parkinson's disease as mice don't show the same disease symptoms as people. "To what degree the rat will replace the mouse remains to be seen," says Iva Morse, a corporate vice president for research model services at Charles River Laboratories.
Dec 28, 2010