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DrugMonkey goes into a bit more detail about the new NIH grant application policy that limits applicants to one amendment (currently applications are limited to two amendments, as established in 1996). The blogger wades through some data and is still at a loss to understand how a new limit will "ensure earlier funding of high-quality applications and improve efficiencies in the peer review system" as the NIH press release says. "So I'm still at a loss. I don't yet see where anything in the available data predicts that original, unrevised grant applications are going to have better success," blogs DrugMonkey.