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Putting Down the Odds

Steve Murphy at Gene Sherpas predicts that Complete Genomic will win the Archon X Prize for Genomics this year, but in the comments, Keith Robison is doubtful. "Complete Genomics is impressive, but the X-prize criteria are pretty onerous — I doubt they or PacBio will be gunning for it for at least 2 years," Robison writes. Daniel MacArthur also takes up the idea at his blog where he notes that those criteria include 98 percent coverage of each of the test genomes and no more than one error per 100,000 bases sequenced. Furthermore, MacArthur points out, to qualify for the prize this year, teams have to be registered by January 15th.

The Scan

New Study Highlights Role of Genetics in ADHD

Researchers report in Nature Genetics on differences in genetic architecture between ADHD affecting children versus ADHD that persists into adulthood or is diagnosed in adults.

Study Highlights Pitfall of Large Gene Panels in Clinical Genomic Analysis

An analysis in Genetics in Medicine finds that as gene panels get larger, there is an increased chance of uncovering benign candidate variants.

Single-Cell Atlas of Drosophila Embryogenesis

A new paper in Science presents a single-cell atlas of fruit fly embryonic development over time.

Phage Cocktail Holds Promise for IBD

Researchers uncovered a combination phage therapy that targets Klebsiella pneumonia strains among individuals experiencing inflammatory bowel disease flare ups, as they report in Cell.