The Gene Sherpa follows up on news that Kaiser Permanente and the University of California, San Francisco, won a $24.8 million NIH grant to use data and biospecimens from 100,000 Kaiser members in a large-scale study of the health implications of genetic and environmental interactions. Blogger Steve Murphy posits that this could "serve as a prototype" for the kind of biobank Francis Collins has advocated, but cautions that "this will be a huge boondoggle unless done very, very carefully."