Derek Lowe blogs at In the Pipeline about the potential future of drug discovery — once research moves beyond its limited, and limiting, work targeting drugs that only bind proteins. He reminds us of the universe of possibilities: proteins interacting with other proteins, DNA, RNA, carbohydrates, and lipids, which are some of the many targets that have yet to be fully explored for therapeutic value.

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Though many details have yet to be worked out, the draft deal for the UK's withdrawal from the EU is giving researchers some hints for what they can expect, Nature News says.

DNA testing has solved a 100-year-old mystery contained in the skull and teeth samples of a now-extinct monkey that once inhabited Jamaica, Gizmodo reports.

As the UN ponders a ban on gene drives, one malaria researchers says there are less dramatic ways to fight the disease in Africa than unleashing GM mosquitoes on a whole continent.

In Nature this week: an improved reference genome of the Aedes aegypti mosquito, genomes of four species of truffles, and more.