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Derek Lowe blogs at In the Pipeline about the potential future of drug discovery — once research moves beyond its limited, and limiting, work targeting drugs that only bind proteins. He reminds us of the universe of possibilities: proteins interacting with other proteins, DNA, RNA, carbohydrates, and lipids, which are some of the many targets that have yet to be fully explored for therapeutic value.

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Bloomberg reports that the DNA-for-cash deal reported in Kentucky might be a more widespread scam.

St. Jude Children's Research Hospital scientists have treated infants with X-linked severe combined immunodeficiency using gene therapy in an early phase study.

St. Louis Public Radio reports that some African Americans are turning to DNA ancestry testing to help guide genealogical searches.

In Nature this week: a genomic analysis of the snailfish Pseudoliparis swirei, ancient DNA analysis gives insight into the introduction of farming to England, and more.