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Genome Protection

Massachusetts state legislators have introduced a new bill called the Massachusetts Genetic Bill of Rights, reports Genomics Law Report's Susan Huber and Dan Vorhaus. The proposed bill establishes property right and privacy rights for personal genetic information and protects individuals from having their genetic information used against them, as in genetic profiling, Huber and Vorhaus add. The bill proposes to fill the gaps in genetic rights left by limitations in GINA and HIPAA. Among the bill's provisions: personal genomes would be considered "personal property" and insurers wouldn't be allowed to use a person's genetic makeup against them in matters of long-term care or life insurance, which GINA does not provide for. As Turna Ray notes in our sister publication Pharmacogenomics Reporter, the bill already has the support of several state senators and representatives.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.