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Promoting Research Integrity in the UK

Nature's The Great Beyond Blog says that "the UK should establish a one-stop shop for advice on research integrity to rebuild public confidence undermined by a series of scandals," based on a new Research Integrity Futures Working Group report. The organization's chair, Janet Finch, told Nature that the group would like to see their proposed body — which "would have no regulatory function but could offer advice and collect data on integrity issues — funded £400,000 a year by the government. "Current UK arrangements are sometimes portrayed as less than transparent, with examples of bad practice 'swept under the carpet' ... And there is limited evidence to contradict that view," the report reads.

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.