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Predicting Problems: Genetic Markers Show Whether Antidepressants Might Backfire

Since the FDA slapped black-box warnings in 2005 on certain antidepressants associated with triggering suicidal thinking in kids and teenagers, scientists have been trying to figure out if there's genetic susceptibility for that. Two recent studies have come out, one led by Francis McMahon at the NIMH and the other by Roy Perlis at Harvard, implicating markers on three separate genes that might influence suicidal thinking for those taking the common SSRI citalopram, sold under the brand name Celexa.

The Scan

Tens of Millions Saved

The Associated Press writes that vaccines against COVID-19 saved an estimated 20 million lives in their first year.

Supersized Bacterium

NPR reports that researchers have found and characterized a bacterium that is visible to the naked eye.

Also Subvariants

Moderna says its bivalent SARS-CoV-2 vaccine leads to a strong immune response against Omicron subvariants, the Wall Street Journal reports.

Science Papers Present Gene-Edited Mouse Models of Liver Cancer, Hürthle Cell Carcinoma Analysis

In Science this week: a collection of mouse models of primary liver cancer, and more.