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Pre-de-Extinction

While it would be quite a sight to see extinct animals like the woolly mammoth again walking the earth, bringing back species from beyond the grasp of extinction — as number of researchers and bloggers have been discussing lately — may not be the best use of such innovations, Scientific American says.

"De-extinction" techniques may be better applied to increase the genetic diversity of species on the verge of extinction. "For example, extinct versions of genes could be reintroduced into species and subspecies that have lost a dangerous amount of genetic diversity, such as the black-footed ferret and the northern white rhino," Scientific American says. "Such investigations, however, should be conducted under the mantle of preserving modern biodiversity rather than conjuring extinct species from the grave."

The Scan

RNA Editing in Octopuses Seems to Help Acclimation to Shifts in Water Temperature

A paper in Cell reports that octopuses use RNA editing to help them adjust to different water temperatures.

Topical Compound to Block EGFR Inhibitors May Ease Skin Toxicities, Study Finds

A topical treatment described in Science Translational Medicine may limit skin toxicities seen with EGFR inhibitor therapy.

Dozen Genetic Loci Linked to Preeclampsia Risk in New GWAS

An analysis of genome-wide association study data in JAMA Cardiology finds genetic loci linked to preeclampsia that have ties to blood pressure.

Cancer Survival Linked to Mutational Burden in Pan-Cancer Analysis

A pan-cancer paper appearing in JCO Precision Oncology suggests tumor mutation patterns provide clues for predicting cancer survival that are independent of other prognostic factors.