Writing in Nature Biotechnology, a team led by investigators at the US National Biodefense Analysis and Countermeasures Center this week presents "a correction algorithm and assembly strategy that uses short, high-fidelity sequences to correct the error in single-molecule sequences." To demonstrate the utility of this approach, the researchers applied it to reads generated by a PacBio RS platform from phage, prokaryotic and eukaryotic whole genomes, including the previously unsequenced

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