The latest issue of Nucleic Acids Research has a free-access review piece from Clyde Hutchison at the J. Craig Venter Institute that gives a nice background on the history of DNA sequencing. And if history isn't your thing, he includes sections on next-gen sequencing and where he thinks all of this is going. To wit: The currently popular vision that an investigator with a single benchtop machine could replace a large sequencing center can only be realized with increases in the productivity of computers and bioinformaticians even more dramatic than that expected for sequencers. It appears that for our individual $1000 genome sequences to be truly useful, fundamental advances in computation and bioinformatics will be essential.
Platitude of the Day: You Can't Know Where You're Going If You Don't Know Where You've Been
Oct 26, 2007
What's Popular?