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Platitude of the Day: You Can't Know Where You're Going If You Don't Know Where You've Been

The latest issue of Nucleic Acids Research has a free-access review piece from Clyde Hutchison at the J. Craig Venter Institute that gives a nice background on the history of DNA sequencing. And if history isn't your thing, he includes sections on next-gen sequencing and where he thinks all of this is going. To wit:

The currently popular vision that an investigator with a single benchtop machine could replace a large sequencing center can only be realized with increases in the productivity of computers and bioinformaticians even more dramatic than that expected for sequencers. It appears that for our individual $1000 genome sequences to be truly useful, fundamental advances in computation and bioinformatics will be essential.

 

The Scan

Rise of BA.5

The New York Times reports that the Omicron subvariant BA.5 has become the dominant version of SARS-CoV-2 in the US.

UK Health Secretary Resigns

Sajid Javid, the UK health secretary, resigned along with Chancellor Rishi Sunak, saying they cannot work with Prime Minister Boris Johnson's government, CNN reports.

Clones From Freeze-Dried Cells

A team in Japan has cloned mice from freeze-dried skin cells, according to the Guardian.

Genome Research Papers on Craniosynostosis, Macaque Retrotransposition, More

In Genome Research this week: structural variants in craniosynostosis, LINE-1 activity in rhesus macaque brain, and more.