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A Place to Discuss the Science of the Flu

The Public Library of Science launched a new website, PLoS Currents. According to a post by Harold Varmus, it is "a new and experimental website for the rapid communication of research results and ideas." The first of the PLoS Currents sites will focus on influenza and contributions can range from epidemiology to genomics and from virology to policy. Submissions will not be subject to "in-depth peer review" but will be screened by a panel led by Penn State's Eddie Holmes and Mount Sinai's Peter Palese. The site will be given a unique NCBI identifier so it can be easily cited. "Given that the contributions to PLoS Currents are not peer-reviewed in detail, however, the results and conclusions must be regarded as preliminary," Varmus writes. "In time, it is therefore likely that PLoS Currents contributors will submit their work for publication in a formal journal."

The Scan

Study Links Genetic Risk for ADHD With Alzheimer's Disease

A higher polygenic risk score for attention-deficit/hyperactivity disorder is also linked to cognitive decline and Alzheimer's disease, a new study in Molecular Psychiatry finds.

Study Offers Insights Into Role of Structural Variants in Cancer

A new study in Nature using cell lines shows that structural variants can enable oncogene activation.

Computer Model Uses Genetics, Health Data to Predict Mental Disorders

A new model in JAMA Psychiatry finds combining genetic and health record data can predict a mental disorder diagnosis before one is made clinically.

Study Tracks Off-Target Gene Edits Linked to Epigenetic Features

Using machine learning, researchers characterize in BMC Genomics the potential off-target effects of 19 computed or experimentally determined epigenetic features during CRISPR-Cas9 editing.