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Pharma Capitalizes on Cancer Genetics

Pharmaceutical companies are starting to design clinical trials for cancer treatments using data on cancer genetics to pinpoint which patients are more likely to respond to each drug, according to MIT's Technology Review. Emily Singer writes that doctors are hoping to be able to treat patients with specific drugs according to the genetic profile of their illness, and which mutations are affecting their individual tumors. Researchers at the Wellcome Trust Sanger Institute's Cancer Genome Project are collaborating with researchers at Massachusetts General Hospital to screen 400 compounds on 1,000 cancer cell lines derived from various tumors, Singer says. "Collectively, the cells possess about 70 cancer-linked genetic mutations, about 50 to 80 percent of the mutations that have been uncovered to date," she adds.

The Scan

Alzheimer's Risk Gene Among Women

CNN reports that researchers have found that variants in MGMT contribute to Alzheimer's disease risk among women but not men.

Still Hanging Around

The Guardian writes that persistent pockets of SARS-CoV-2 in the body could contribute to long COVID.

Through a Little Spit

Enteric viruses like norovirus may also be transmitted through saliva, not just the fecal-oral route, according to New Scientist.

Nature Papers Present Method to Detect Full Transcriptome, Viruses Infecting Asgard Archaea, More

In Nature this week: VASA-seq approach to detect full transcriptome, analysis of viruses infecting Asgard archaea, and more.