Over at the Sandwalk, Larry Moran blogs about the thousands of unknown genes in sequenced genomes -- "'unknown' in the sense that no function has been assigned to their protein products." The catalyst for the post is a PLoS One paper on Neurospora crassa, which has some "9,000 protein-encoding genes and more than half of them have not been annotated," Moran writes. "The question is: are the unknown genes confined to Neurospora and its close relatives?

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Jay Shendure and his colleagues have developed a new method to more comprehensively identify human cell types, the NY Times reports.

Researchers in the UK and Japan have shown that infertility in mice with three sex chromosomes can be overcome, according to the Guardian.

China is embracing preimplantation genetic diagnosis, Nature News reports. 

In PLOS this week: host genetic factors associated with cervical neoplasia progression, population patterns for an ancient flowering rainforest plant, and more.