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Pearl Necklaces and Gene Expression

At the Daily Transcript, Alex Palazzo gives a rundown of how DNA is organized and how that organization affects gene expression -- it's not all epigenetics and noncoding RNAs (remember promoters and enhancers?). He starts by describing the "pearl necklace" of DNA and histones, then goes into how those nucleosomes can be modified and how those modifications influence gene expression. "You see it is a very complicated mess, but one that allows for a very dynamic regulation of gene expression," Palazzo writes.

The Scan

Boosters Chasing Variants

The New York Times reports that an FDA advisory panel is to weigh updated booster vaccines for COVID-19.

Not Yet

The World Health Organization says monkeypox is not yet a global emergency, the Washington Post reports.

More Proposed for Federal Research

Science reports that US House of Representatives panels are seeking to increase federal research funding.

PLOS Papers on Breast Cancer Metastasis, Left-Sided Cardiac Defects, SARS-CoV-2 Monitoring

In PLOS this week: link between breast cancer metastasis and CLIC4, sequencing analysis of left-sided cardiac defects, and more.