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PCR Vendors, Skip to the Next Post

In a paper published online yesterday in Nature Methods, senior author Richard Gibbs and collaborators at Baylor and NimbleGen present a direct-selection technique for DNA sequences that does not require using PCR. The work took place using NimbleGen arrays and a 454 sequencer. "We combined these new developments to enable the efficient targeted capture and sequencing of specific DNA sequences from complex genomes to provide an alternative to PCR-based methods," the authors write.

 

The Scan

mRNA-Based Vaccine on the Way in China

China may soon have its own mRNA-based vaccine, according to Nature News.

Arranged Killing, Fraud Alleged by Prosecutors

The Wall Street Journal reports that prosecutors allege that the co-founder of a biotech arranged to have a business associate who threatened to expose him as a fraud killed.

Whirlwind Decade of CRISPR

The New York Times looks back at the 10 years since the University of California, Berkeley's Jennifer Doudna and her colleagues published their CRISPR paper.

PNAS Papers on Blue Cone Monochromacy Structural Variants, HIV-1 Mutant, T-ALL

In PNAS this week: structural variants linked to blue cone monochromacy, HIV-1 variants affecting the matrix protein p17, and more.