Paying for Play?

In response to a reader's question, Dr. Isis discusses why scientists sometimes have to pay to be published. She writes that originally, scientists submitted their work to journals that their academic libraries, departments, or even they themselves subscribed to; those subscription fees kept the journals funded. Then the rise of public access and open access brought about author fees to defray publication costs, she says.

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The UK's Nuffield Council on Bioethics says genetically modifying human embryos could be morally permissible, according to the Guardian.

A new Nature Biotechnology paper reports that CRISPR-Cas9 gene editing can lead to large deletions or complex rearrangements that could be pathogenic.

The Wall Street Journal likens a prototype developed by Synthetic Genomics to a "biological fax machine."

In PNAS this week: strategy for reactivating Rett syndrome-linked MECP2, small molecules able to suppress Staphylococcus aureus virulence, and more.