Skip to main content
Premium Trial:

Request an Annual Quote

From Parts to Networks

The sequencing of the first human genome provided a "parts list" that needs to be placed into a larger context of how those parts work together, László Barabási from Northeastern University tells NOVA Next.

Barabási and other researchers like Marc Vidal at Dana-Farber Cancer Center and Joseph Loscalzo at Harvard Medical School are looking to make connections between DNA and proteins to see how the parts all fit together and identify what networks are involved in certain diseases.

Barabási says the "diseasome" is like a map of Manhattan in that certain activities tend to cluster like plays on Broadway or trading on Wall Street. They've uncovered, NOVA Next says, some disease modules where genes and proteins involved in a certain disease tend to clump.

"Future medical treatments may not focus on a particular genetic mutation, but rather on the biological routes through which diseases are expressed," NOVA Next adds.

The Scan

NFTs for Genome Sharing

Nature News writes that non-fungible tokens could be a way for people to profit from sharing genomic data.

Wastewater Warning System

Time magazine writes that cities and college campuses are monitoring sewage for SARS-CoV-2, an approach officials hope lasts beyond COVID-19.

Networks to Boost Surveillance

Scientific American writes that new organizations and networks aim to improve the ability of developing countries to conduct SARS-CoV-2 genomic surveillance.

Genome Biology Papers on Gastric Cancer Epimutations, BUTTERFLY, GUNC Tool

In Genome Biology this week: recurrent epigenetic mutations in gastric cancer, correction tool for unique molecular identifier-based assays, and more.