Paging Fred: We Need a Quick Reminder

Keith Robison blogs about Genome Corp, the Rhode Island-based genome sequencing startup that recently got $250,000 in seed funding, and founder Kevin Ulmer. In his musings on sequencing, Robison gets to wondering: what does "Sanger sequencing" really mean? "I generally think of it as electrophoretic resolution of dideoxy-terminated fragments, but if you think a bit it's obvious that Sanger's unique contribution was the terminators; Maxam-Gilbert used the same electrophoretic separation," he writes, noting that this could affect which of the next-gen sequencing techs we think of as Sanger-based.