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Outsmarting HIV With Sys Bio

A team of computational biologists and infectious disease scientists have developed methods to estimate the genetic diversity of virus populations within a single host. Publishing their results recently in PLoS Computational Biology, the researchers used computational analyses on pyrosequencing data from HIV patients with drug-resistant virus strains, and comparing these to 165 sequences of four independent HIV populations, were able to reconstruct the viral population. They hope to apply their methods to vaccine design and antiviral drug therapy.

The Scan

Billions for Antivirals

The US is putting $3.2 billion toward a program to develop antivirals to treat COVID-19 in its early stages, the Wall Street Journal reports.

NFT of the Web

Tim Berners-Lee, who developed the World Wide Web, is auctioning its original source code as a non-fungible token, Reuters reports.

23andMe on the Nasdaq

23andMe's shares rose more than 20 percent following its merger with a special purpose acquisition company, as GenomeWeb has reported.

Science Papers Present GWAS of Brain Structure, System for Controlled Gene Transfer

In Science this week: genome-wide association study ties variants to white matter stricture in the brain, and more.