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One Step of the Pathway

A team of researchers announced its first draft of the genome of Rhodnius prolixus, a vector of Chagas disease transmission, reports SciDev.Net. Chagas disease is caused by a parasite, Trypanosoma cruzi, that is transmitted by triatomine bugs like R. prolixus. "We chose R. prolixus because it has the smallest genome among all bugs from the triatomine family," says Pedro Oliveira from the Federal University of Rio de Janeiro to SciDev.Net. The draft was presented at the International Workshop for Genomic and Triatomine Biology in La Plata, Argentina.

"If we discover why the kissing bug — and not other insects — transmits the parasite we could study the mechanism to inhibit this transmission," adds the National University of La Plata's Rolando Rivera-Pomar.

The Scan

Long COVID-19 Susceptibility Clues Contained in Blood Plasma Proteome

A longitudinal study in eBioMedicine found weeks-long blood plasma proteome shifts after SARS-CoV-2 infection, along with proteomic signatures that appeared to coincide with long Covid risk.

Tibetan Study Finds Adaptive Variant Influencing Skin Pigmentation

With a combination of phenotyping and genetic data, researchers document at PNAS a Tibetan-enriched enhancer variant influencing melanin synthesis and ultraviolet light response.

Domestication Linked to Nervous System Genes in Inbred Mouse Strains

Researchers highlighted more than 300 positively selected genes in domesticated mice, including genes linked to nervous system function or behavior in Genome Biology.

ALS Genetic Testing May Be Informative Across Age Ranges, Study Finds

Researchers in the journal Brain identified clinically actionable variants in a significant subset of older ALS patients, prompting them to point to the potential benefits of broader test use.