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'OK, Now What?'

Pfizer scientists had a "headdesk" moment in October, when German researchers showed that an antidepressant the company markets in Europe doesn't work in humans, even though animal model data showed it to be effective, Scientific American guest blogger SciCurious wrote in November.

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Researchers tie a variant in ADAMTS3 to breathing difficulties in dissimilar dog breeds, according to Discover's D-brief blog.

The Japan Times reports that researchers sequenced the genome of a woman who lived during the Jomon period.

Parents of children with rare genetic disease have to contend with shifts in the interpretation of genetic variants, the Wall Street Journal reports.

In Science this week: single-nucleus RNA sequencing of brain tissue from individuals with autism, and more.