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Not Wanting Her Genome Sequence (Yet)

While more and more individuals talk about the experience of having their genome sequenced, science writer and geneticist Ricki Lewis says she is not ready to receive hers yet.

"A genome sequence is a mega incidentalome, an avalanche of information I don't want," Lewis says in a post on PLOS's DNA Science Blog.

There are also diseases she would not want to learn about, such as brain disorders. "If I can't prevent or delay them, why spend years worrying?"

Plus, she says, there is simply not enough information available to make sense of the results, for example how disease-causing and protective mutations interact. "It's like reading a novel and considering each word in a vacuum, compared to understanding the unfolding story," she writes.

Lewis says she might get her genome done as part of the Personal Genomes Project, a research study, but choose not to learn the results. "After all, I already know the obvious, like Craig Venter knows he's bald and has blue eyes."

The Scan

Two J&J Doses

Johnson & Johnson says two doses of its SARS-CoV-2 vaccine provides increased protection against symptomatic COVID-19, CNN reports.

Pfizer-BioNTech Vaccine Response in Kids

The Pfizer-BioNTech SARS-CoV-2 vaccine in a lower-dose format appears to generate an immune response among children, according to the Washington Post.

Chicken Changes to Prevent Disease

The Guardian writes that researchers are looking at gene editing chickens to help prevent future pandemics.

PNAS Papers on Siberian Dog Ancestry, Insect Reproduction, Hippocampal Neurogenesis

In PNAS this week: ancestry and admixture among Siberian dogs, hormone role in fruit fly reproduction, and more.