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Derek Lowe is used to sketching out compounds that don't yet exist, which he shares in this post at In the Pipeline. But just because there are no literature references doesn't mean a compound is not commercially available for research purposes. He says you "don't have to go that crazy to leave the paved roads behind," as there are many structures that haven't been explored yet.

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A survey by Nature finds that most researchers want scientific meetings to continue virtually or with a virtual component, even after the pandemic ends.

Bloomberg reports that the B.1.351 SARS-CoV-2 viral variant could prompt the formulation of better vaccines.

Certain blood proteins may be able to distinguish COVID-19 patients who will become critically ill from those who will not, the Atlanta Journal-Constitution reports.

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