Not So 'Informed'

A group of ethicists and medical researchers says informed consent has become more about protecting the researcher than protecting the patient, reports Nature News' Daniel Cressey. At the European Forum for Good Clinical Practice conference in Brussels last week, a Belgian think tank warned that the process of informed consent has become an exercise in legal obligation rather than an effort to help trial participants understand the risks and benefits of participation.

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The US Food and Drug Administration has approved Alnylam's RNAi-based therapy Onpattro, according to Stat News.

Harvard Medical School's Seth Cassel and Cigall Kadoch argue in a Baltimore Sun op-ed that the recent TAILORx trial shows the potential of genomic-based medicine.

Researchers in the UK are working on using gene drives to control malaria-carrying mosquitoes, the Telegraph reports.

In PLOS this week: genetic architecture mediating gene expression, metabolomic patterns in multiple myeloma, and more.