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Nostalgia for a Simpler Time

The past two years, Sandra Porter blogs, have changed how people view the genome, particularly concerning how the genome is assembled and how that information is translated to become proteins. She used to think that structural variations weren't so common, but now there are more structural variations "than we would have ever expected," she writes. Also, the old conventional wisdom said that to get a gene expressed, the DNA of that gene was copied into RNA, and that would be sent to the ribosome to be made into protein with the help of three RNAs. "Now … everywhere you look there's some new kind of RNA with some unknown kind of function," Porter says, adding that new technologies are forcing people to look at the world in a new way.

The Scan

Another Resignation

According to the Wall Street Journal, a third advisory panel member has resigned following the US Food and Drug Administration's approval of an Alzheimer's disease drug.

Novavax Finds Its Vaccine Effective

Reuters reports Novavax's SARS-CoV-2 vaccine is more than 90 percent effective in preventing COVID-19.

Can't Be Used

The US Food and Drug Administration says millions of vaccine doses made at an embattled manufacturing facility cannot be used, the New York Times reports.

PLOS Papers on Frozen Shoulder GWAS, Epstein-Barr Effects on Immune Cell Epigenetics, More

In PLOS this week: genome-wide association study of frozen shoulder, epigenetic patterns of Epstein-Barr-infected B lymphocyte cells, and more.