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Nobody's Perfect

A non-genomics researcher mentioned to Mike the Mad Biologist that there was a lot of criticism of the E. coli 104:H4 outbreak sequences, and Mike writes on his blog that he wasn't sure what his colleague was referring to. Then he realized that assessments of the quality of the sequence data could look like criticism of the science to an outsider, even when it's not. With a high-quality sequence, Mike writes that the error rate could be between 1 in 100,000 and 1 in 1,000,000 per base. "That sounds good until you realize that a typical E. coli genome is around five million bases long," Mike says, later adding that "no genome sequence, even a finished one, is perfect. But we can still do good science, even as we recognize the flaws in the data."

The Scan

US Booster Eligibility Decision

The US CDC director recommends that people at high risk of developing COVID-19 due to their jobs also be eligible for COVID-19 boosters, in addition to those 65 years old and older or with underlying medical conditions.

Arizona Bill Before Judge

The Arizona Daily Star reports that a judge is weighing whether a new Arizona law restricting abortion due to genetic conditions is a ban or a restriction.

Additional Genes

Wales is rolling out new genetic testing service for cancer patients, according to BBC News.

Science Papers Examine State of Human Genomic Research, Single-Cell Protein Quantification

In Science this week: a number of editorials and policy reports discuss advances in human genomic research, and more.