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No Two Are (Completely) Alike

In a paper recently published in Nature Genetics, Art Petronis of the Center for Addiction and Mental Health in Toronto led a study to look at genome-wide methylation patterns in identical and fraternal twins. Using 12K CpG island microarrays, his team looked at DNA methylation patterns from cheek swabs, blood samples, and gut biopsies across 114 monozygotic twins and 80 dizygotic twins to find that while identical twins did show significant variation in their epigenetic code, they showed less difference than non-identical twins. A story in the Economist wonders how some methylation is escaping pre-fertilization erasure: "Quite a lot of pre-existing methylation is making its way into the new individual -- and thus providing both a complication to those who try to understand the intricacies of inheritance, and a promising new line of inquiry."

The Scan

Billions for Antivirals

The US is putting $3.2 billion toward a program to develop antivirals to treat COVID-19 in its early stages, the Wall Street Journal reports.

NFT of the Web

Tim Berners-Lee, who developed the World Wide Web, is auctioning its original source code as a non-fungible token, Reuters reports.

23andMe on the Nasdaq

23andMe's shares rose more than 20 percent following its merger with a special purpose acquisition company, as GenomeWeb has reported.

Science Papers Present GWAS of Brain Structure, System for Controlled Gene Transfer

In Science this week: genome-wide association study ties variants to white matter stricture in the brain, and more.