About 150 people descended on Cold Spring Harbor Laboratory last week for the first Personal Genomes meeting. MikeM has a post on 23andMe's Spittoon blog describing the proceedings of the first half of the conference, which kicked off with talks from Jim Watson, Francis Collins, and Mary-Claire King. GTO enjoyed the conference as well, but we were a little surprised by how many mainstream-media journalists were in attendance.

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The UK's Nuffield Council on Bioethics says genetically modifying human embryos could be morally permissible, according to the Guardian.

A new Nature Biotechnology paper reports that CRISPR-Cas9 gene editing can lead to large deletions or complex rearrangements that could be pathogenic.

The Wall Street Journal likens a prototype developed by Synthetic Genomics to a "biological fax machine."

In PNAS this week: strategy for reactivating Rett syndrome-linked MECP2, small molecules able to suppress Staphylococcus aureus virulence, and more.