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No, There Were No Spit Parties on Campus

About 150 people descended on Cold Spring Harbor Laboratory last week for the first Personal Genomes meeting. MikeM has a post on 23andMe's Spittoon blog describing the proceedings of the first half of the conference, which kicked off with talks from Jim Watson, Francis Collins, and Mary-Claire King. GTO enjoyed the conference as well, but we were a little surprised by how many mainstream-media journalists were in attendance. Looks like this whole personal genomics thing really is getting the public's attention.

 

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.