No Imagination

Is innovation becoming a lost art in the pharmaceutical industry? A new survey of 282 pharmaceutical executives, done at the behest of clinical research organization Quintiles, found that 54 percent consider innovation to be a leading priority and 49 percent rank their overall innovation strategy as, at best, moderately effective, says Pharmalot's Ed Silverman.

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The US Food and Drug Administration has approved Alnylam's RNAi-based therapy Onpattro, according to Stat News.

Harvard Medical School's Seth Cassel and Cigall Kadoch argue in a Baltimore Sun op-ed that the recent TAILORx trial shows the potential of genomic-based medicine.

Researchers in the UK are working on using gene drives to control malaria-carrying mosquitoes, the Telegraph reports.

In PLOS this week: genetic architecture mediating gene expression, metabolomic patterns in multiple myeloma, and more.