At the annual meeting of the Association for Molecular Pathology this week, the Chinese University of Hong Kong's Dennis Lo spoke about bringing non-invasive prenatal diagnostic testing to the clinic, using next-generation sequencing. Although it is now routine in many parts of the world to test for X-linked disorders, some women choose to undergo invasive prenatal diagnostic testing for Down syndrome, Lo said. Testing for Down syndrome using the mother's blood is more challenging than testing for X-linked disorders in that manner is.