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NIH, SBIR, and Stimulus Funds

US Senator Mary Landrieu (D–LA) doesn't like that the NIH was exempt from paying its 2.5 percent tax on its stimulus funds that every federal agency usually pays from their research budget to fund the Small Business Innovation Research program, reports ScienceInsider. At an oversight hearing, Landrieu told NIH's acting head of extramural research, Sally Rockey, how stimulus funds have affected small businesses. Rockey then promised Landrieu that NIH is "committed" to giving the SBIR its share of funds and she estimates that NIH will small businesses about $200 million out of its stimulus funds.

The Scan

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.

TB Resistance Insights Gleaned From Genome Sequence, Antimicrobial Response Assays

Researchers in PLOS Biology explore M. tuberculosis resistance with a combination of sequencing and assays looking at the minimum inhibitory concentrations of 13 drugs.

Mendelian Disease Genes Prioritized Using Tissue-Specific Expression Clues

Mendelian gene candidates could be flagged for further functional analyses based on tissue-specific transcriptome and proteome profiles, a new Journal of Human Genetics paper says.

Single-Cell Sequencing Points to Embryo Mosaicism

Mosaicism may affect preimplantation genetic tests for aneuploidy, a single-cell sequencing-based analysis of almost three dozen embryos in PLOS Genetics finds.