The NIH open access policy has reached its first birthday and Gavin Baker, assistant editor of Open Access News, has a guest blog at Science Progress to discuss it. Since the policy went into effect, Baker says that PubMed submissions were never lower than 2,500 a month, as compared to 1,500 in December 2007. He also says that Elsevier, which opposes the policy, had an 11 percent increase in profits during 2008.

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The UK's Nuffield Council on Bioethics says genetically modifying human embryos could be morally permissible, according to the Guardian.

A new Nature Biotechnology paper reports that CRISPR-Cas9 gene editing can lead to large deletions or complex rearrangements that could be pathogenic.

The Wall Street Journal likens a prototype developed by Synthetic Genomics to a "biological fax machine."

In PNAS this week: strategy for reactivating Rett syndrome-linked MECP2, small molecules able to suppress Staphylococcus aureus virulence, and more.