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NIH: Job Creator

A new report from the US Government Accountability Office shows that the $8.2 billion NIH received from the government during the 2009 stimulus created at least 21,000 jobs, reports ScienceInsider's Jocelyn Kaiser. When NIH received the funds, the agency's acting director Raynard Kington told Congress that the additional money would help create jobs. The GAO report shows that 12,000 full-time equivalent positions were initially created in December 2009, a number that grew for nine months until it hit 21,000 in June 2011, Kaiser says, or about one FTE for each of the 21,500 grants NIH awarded during that time. NIH says once all the data is compiled, it will shows that the stimulus money supported up to 54,000 FTEs. However, Kaiser adds, the report doesn't show what will happen to these jobs after the stimulus money runs out. Another report is expected sometime next year to discuss that in more detail.

The Scan

Expanded Genetic Testing Uncovers Hereditary Cancer Risk in Significant Subset of Cancer Patients

In Genome Medicine, researchers found pathogenic or likely pathogenic hereditary cancer risk variants in close to 17 percent of the 17,523 patients profiled with expanded germline genetic testing.

Mitochondrial Replacement Therapy Embryos Appear Largely Normal in Single-Cell 'Omics Analyses

Embryos produced with spindle transfer-based mitochondrial replacement had delayed demethylation, but typical aneuploidy and transcriptome features in a PLOS Biology study.

Cancer Patients Report Quality of Life Benefits for Immune Checkpoint Inhibitors

Immune checkpoint inhibitor immunotherapy was linked in JAMA Network Open to enhanced quality of life compared to other treatment types in cancer patients.

Researchers Compare WGS, Exome Sequencing-Based Mendelian Disease Diagnosis

Investigators find a diagnostic edge for whole-genome sequencing, while highlighting the cost advantages and improving diagnostic rate of exome sequencing in EJHG.