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The NIH Isn't the Only Agency That Needs Some Padding

FDA Science and Mission at Risk, a report submitted by an independent advisory board, has released a "horrifying" analysis of why the FDA seems to be at least one weak link in a chain (read: NIH) of underfunded scientific government agencies. An article in USA Today, pointed out by Deepak Singh, says that the "long list of ailments" is caused by underfunding and an overburdened workforce. "In addition to advocating for increased funding, the report recommends that the FDA, among other things, invest in IT, centralize science programs, create new science directors and hire more high-quality talent," says the article.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.