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NIH Budget Sausage-Making

The 2010 NIH budget is still being hammered out and the Senate appropriations committee has approved a 1.4 percent increase, bringing the budget to up by $442 million to $31.8 billion, reports Science Insider. The labor, health and human services subcommittee agreed with President Obama and decided that NIH did not need more money as the stimulus bill gave it $10 billion. The bill does not include funding for specific diseases that Obama had requested. The House version of the bill had approved a 3.1 percent increase. The two bills will be reconciled before moving on to the President's desk.

The Scan

UCLA Team Reports Cost-Effective Liquid Biopsy Approach for Cancer Detection

The researchers report in Nature Communications that their liquid biopsy approach has high specificity in detecting all- and early-stage cancers.

Machine Learning Improves Diagnostic Accuracy of Breast Cancer MRI, Study Shows

Combining machine learning with radiologists' interpretations further increased the diagnostic accuracy of MRIs for breast cancer, a Science Translational Medicine paper finds.

Genome Damage in Neurons Triggers Alzheimer's-Linked Inflammation

Neurons harboring increased DNA double-strand breaks activate microglia to lead to neuroinflammation like that seen in Alzheimer's disease, a new Science Advances study finds.

Long COVID-19 Susceptibility Clues Contained in Blood Plasma Proteome

A longitudinal study in eBioMedicine found weeks-long blood plasma proteome shifts after SARS-CoV-2 infection, along with proteomic signatures that appeared to coincide with long Covid risk.