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Next-Gen Sequencing: Enough for a Miniseries?

MIT's Technology Review follows up its first article on 454's sequencing technology with a second installment. Part II goes into the collaboration of 454 with the Max Planck Institute to sequence a 1-million-base-pair portion of the Neanderthal genome, as well as other practical medical applications such as single molecule sequencing to discover cancer mutations and George Church's Personal Genome Project.

The Scan

Purnell Choppin Dies

Purnell Choppin, a virologist who led the Howard Hughes Medical Institute, has died at 91, according to the Washington Post.

Effectiveness May Decline, Data From Israel Suggests

The New York Times reports that new Israeli data suggests a decline in Pfizer-BioNTech SARS-CoV-2 vaccine effectiveness against Delta variant infection, though protection against severe disease remains high.

To See Future Risk

Slate looks into the use of polygenic risk scores in embryo screening.

PLOS Papers on Methicillin-Resistant Staphylococcus, Bone Marrow Smear Sequencing, More

In PLOS this week: genomic analysis of methicillin-resistant Staphylococcus pseudintermedius, archived bone marrow sequencing, and more.