Next-gen Challenges

Back in the early days of next-gen sequencing, when the Solexa brand was still around, some serious challenges faced the field, MassGenomics' Dan Koboldt writes. Bioinformatics algorithms for capillary-based sequencing didn't scale, reads were shorter and error-prone, tools were expensive and hard to access, and few people had any experience with NGS.

Get the full story

This story is free
for registered users

Registering provides access to this and other free content.

Register now.

Already have an account?
Login Now.

Dog DNA testing finds that some purebreds might not truly be purebreds, Inside Edition reports.

Mary Beckerle has returned as director of the Huntsman Cancer Institute, according to ScienceInsider.

Smithsonian Magazine reports that environmental DNA sampling can be used to track elusive organisms.

In Genome Research this week: repetitive satellite DNA in the fruit fly, transcriptome map assembly pipeline, and more.