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Harvard's Derrick Rossi and his colleagues report in Cell Stem Cell on a way to use synthetic messenger RNAs to have differentiated human cells to regain their pluripotency. Rather than relying on viruses, messenger RNA delivers the four proteins needed to induce pluripotency.

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Bloomberg reports AstraZeneca may conduct another study of its candidate SARS-CoV-2 vaccine after dosing error.

Moderna is applying for an Emergency Use Authorization for its coronavirus vaccine, according to the New York Times.

The National Health Service is to conduct a trial of Grail's blood-based screening test for cancer.

In PLOS this week: somatic mutation patterns of glioblastomas among Lebanese patients, phenome-wide study using UK Biobank data, and more.