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A New Way

A new approach to studying bacteria bypasses the petri dish, but still allows researchers to get lots of sequencing information, reports Discover's 80beats blog. "Pairing a new algorithm with an earlier technique, scientists from the Venter Institute and their collaborators can now get all that information from a single cell," 80beats says. Roger Lasken and his colleagues report in Nature Biotechnology on "algorithm tailored for short-read data from single cells that improves assembly through the use of a progressively increasing coverage cutoff." The researchers used their approach to sequence a single bacterial cell from an ocean sample. 80beats says that this approach is "a perfect match for [organisms that cannot be cultured], and we can expect further papers from this group detailing what they find in everything from sea water to soil to human skin."

Our sister publication GenomeWeb Daily News has more on this work here.

The Scan

Study Reveals New Details About Genetics of Major Cause of Female Infertility

Researchers in Nature Medicine conducted a whole-exome sequencing study of mote than a thousand patients with premature ovarian insufficiency.

Circulating Tumor DNA Shows Potential as Biomarker in Rare Childhood Cancer

A study in the Journal of Clinical Oncology has found that circulating tumor DNA levels in rhabdomyosarcoma may serve as a biomarker for prognosis.

Study Recommends Cancer Screening for Dogs Beginning Age Seven, Depending on Breed

PetDx researchers report in PLOS One that annual cancer screening for dogs should begin by age seven.

White-Tailed Deer Harbor SARS-CoV-2 Variants No Longer Infecting Humans, Study Finds

A new study in PNAS has found that white-tailed deer could act as a reservoir of SARS-CoV-2 variants no longer found among humans.