The sequester, which is set to go into effect at the end of this week if US lawmakers don't come to an agreement to avoid the cuts, will lead to a 5.1 percent, or $1.6 billion, decrease to the National Institutes of Health budget. New grants, USA Today reports, would be particularly affected by the cuts.

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In Science this week: swapping yeast genes with human orthologs to study conservation of function, and more.

Hong Kong is using DNA phenotyping to shame litterers.

A study appearing in Cell suggests some metastatic castration-resistant prostate cancer patients could benefit from PARP inhibitor therapy.

NIH's Francis Collins writes that scientific advances are poised to help populations all over the world, but more scientists are needed to keep the momentum.