The sequester, which is set to go into effect at the end of this week if US lawmakers don't come to an agreement to avoid the cuts, will lead to a 5.1 percent, or $1.6 billion, decrease to the National Institutes of Health budget. New grants, USA Today reports, would be particularly affected by the cuts.

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In PNAS this week: rare variants linked to bleeding disorder, comparison of whole-exome and whole-genome sequencing, and more.

George Church tells The Sunday Times that his group has inserted some woolly mammoth genes into elephant cells.

A Scientific Reports editor resigns over a new policy at the journal allowing researchers to pay to fast track the peer review of their manuscripts, and poll.

The National Cancer Institute's Harold Varmus discusses the state of cancer research with the New York Times.