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A New Place to Experiment

For $150 a month, anyone near Sunnyvale, Calif., can become a member of BioCurious, a community biotech research lab, writes Geek.com's Ray Walters. According to the lab's Web site, it is equipped with an autoclave as well as equipment for electrophoresis and PCR, and the lab offers classes. "For those who aspire to be bio-chemists and can't afford to build a lab of their own, a solution now exists to conduct research on the cheap," Walters writes, later adding that "BioCurious needs to be applauded for creating a space in which innovation can happen in a communal atmosphere. It is this kind of wide open experimentation and idea sharing that creates new and awesome innovation."

The Scan

CRISPR Screens Reveal Heart Attack-Linked Gene

Researchers in PLOS Genetics have used CRISPR screens to home in on variants associated with coronary artery disease that affect vascular endothelial function.

Meta AI Computer Model Rapidly Predicts Hundreds of Millions of Metagenomic Proteins

Meta AI researchers describe in Science a new large language model that can predict the structures of millions of metagenomic proteins.

Hutch Team Develops Platform for Assessing Impact of SARS-CoV-2 Spike Mutations

The approach described in Cell relies on lentiviral pseudotyping for mutational scanning, which the researchers applied to the SARS-CoV-2 spike protein.

Potential New Therapeutic Target for Rheumatoid Arthritis Discovered

Researchers report in the American Journal of Human Genetics that SNPs implicated in rheumatoid arthritis often regulate the expression of the inflammation-related SPRED2 gene.