In a primer, Edward Marcotte from the University of Texas walks readers through the basics of shotgun proteomics. After describing how to break up proteins into smaller pieces and how to run spectra through different databases, he says that "one area in which shotgun proteomics shows particular promise is the large-scale identification of post-translational modifications of proteins."

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The London School of Economics' Daniele Fanelli argues at the Proceedings of the National Academy of Sciences that the reproducibility crisis in science isn't as dire as some say.

A team of researchers in Portugal has examined the genomic basis for racing pigeons' athleticism and navigational skills, finding it's likely polygenic.

Wired reports that diagnostic firms continue to seek, post-Theranos, the ability to diagnose diseases from small amounts of blood.

In Science this week: analysis of DNA from ancient North Africans, and more.