Skip to main content
Premium Trial:

Request an Annual Quote

The Real-time In-depth-ome

Stanford researcher Michael Snyder has been studying his own genome for two years, and now the results of his study have been published in Cell, reports Popular Science's Rebecca Boyle. Snyder and his team have been studying his genome, transcriptome, metabolome, and proteome in an effort to make as detailed a personal 'omics profile as possible. "They watched in real time and at the molecular level as viruses attacked his cells, and they figured out, to their shock, that he was prone to developing type 2 diabetes. And then they watched him develop it," Boyle says. "It's the first study to follow the molecular processes of sickness and health in one individual, and as such it's a major breakthrough for personalized medicine. It's also the first real-time view of the birth of a disease that afflicts millions of people."

With a bit of tongue in cheek, Nature News' Carina Dennis calls the study "the rise of the narciss-ome," adding that the future of personalized medicine "can be glimpsed today" in Snyder's paper. "As a proof-of-principle example of personalized genomic medicine, it is distinct from other studies because it applies whole-genome diagnostics to a healthy person rather than to individuals with disease," she says.

Daily Scan's sister publication, GenomeWeb Daily News, has more on Snyder's study here.

The Scan

Study Finds Sorghum Genetic Loci Influencing Composition, Function of Human Gut Microbes

Focusing on microbes found in the human gut microbiome, researchers in Nature Communications identified 10 sorghum loci that appear to influence the microbial taxa or microbial metabolite features.

Treatment Costs May Not Coincide With R&D Investment, Study Suggests

Researchers in JAMA Network Open did not find an association between ultimate treatment costs and investments in a drug when they analyzed available data on 60 approved drugs.

Sleep-Related Variants Show Low Penetrance in Large Population Analysis

A limited number of variants had documented sleep effects in an investigation in PLOS Genetics of 10 genes with reported sleep ties in nearly 192,000 participants in four population studies.

Researchers Develop Polygenic Risk Scores for Dozens of Disease-Related Exposures

With genetic data from two large population cohorts and summary statistics from prior genome-wide association studies, researchers came up with 27 exposure polygenic risk scores in the American Journal of Human Genetics.