Skip to main content
Premium Trial:

Request an Annual Quote

The Mouse with the Elephant's Memory

Scientists at St. Andrew's University report in the journal Molecular and Cellular Neuroscience that they have genetically engineered mice in which the symptoms of Alzheimer's disease are sent into reverse, according to a news piece in the Guardian. They engineered the mice to produce what they call a "decoy" protein that binds to amyloid protein, preventing amyloid from binding to ABAD, and thereby preventing the disease from actively destroying nerve cells.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.