Standards Needed

The Utah Foundation for Biomedical Research's Gholson Lyon was busy in 2009, trying to identify the genetic causes behind a rare disease affecting baby boys in a family in Ogden, Utah. But, as he says in a Nature commentary, this week, he was hesitant to tell the family what he found because the research he did didn't follow the protocols required for validated clinical testing, and he wasn't sure the individual results were accurate.

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Researchers hope to tease out the signature effects that different carcinogens leave on the genome to determine their contributions to disease, Mosaic reports.

An Imperial College London-led team reports that it was able to use a gene drive to control a population of lab mosquitos.

The Wall Street Journal looks into the cost of new gene therapies.

In PNAS this week: genomic effects of silver fox domestication, limited effect of mitochondrial mutations on aging in fruit flies, and more.