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ScienceInsider looks at the 2011 NIH budget to determine whether Francis Collins is favoring big science over single-investigator grants. Collins is emphasizing his five themes — high-throughput technologies, translational science, health care reform, global health, and reinvigorating biomedical research — and those areas have received large increases in the budget proposal. However, in 2011 NIH will fund 199 fewer research project grants will be funded.

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