Skip to main content
Premium Trial:

Request an Annual Quote

Molecular Imaging on the Horizon

An article in Technology Review takes a closer look at the nascent field of molecular imaging. Scientists at the NCI and the University of Tokyo designed a pH-sensitive fluorescent probe to seek out and grab on to specific receptors on a tumor's surface and light up only when the probe has made it inside a cancer cell. They tested the probe on HER2-positive tumors in mice and found that the probe detected tumors with 99 percent accuracy compared to an "always on" probe, which only detected 85 percent of the tumors. "This specific system may have limited application, especially in regards to taking this forward into the clinic," says Scott Hilderbrand, a scientist at Massachusetts General Hospital's Center for Molecular Imaging Research. "But the concept and approach are definitely very relevant towards the area of enhanced tumor detection at the molecular level."

The Scan

Genetic Tests Lead to Potential Prognostic Variants in Dutch Children With Dilated Cardiomyopathy

Researchers in Circulation: Genomic and Precision Medicine found that the presence of pathogenic or likely pathogenic variants was linked to increased risk of death and poorer outcomes in children with pediatric dilated cardiomyopathy.

Fragile X Syndrome Mutations Found With Comprehensive Testing Method

Researchers in Clinical Chemistry found fragile X syndrome expansions and other FMR1 mutations with ties to the intellectual disability condition using a long-range PCR and long-read sequencing approach.

Team Presents Strategy for Speedy Species Detection in Metagenomic Sequence Data

A computational approach presented in PLOS Computational Biology produced fewer false-positive species identifications in simulated and authentic metagenomic sequences.

Genetic Risk Factors for Hypertension Can Help Identify Those at Risk for Cardiovascular Disease

Genetically predicted high blood pressure risk is also associated with increased cardiovascular disease risk, a new JAMA Cardiology study says.