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A Mixed Bag

Times are still difficult for many biotechs, but Ed Silverman writes at Pharmalot that the situation is actually a bit variable. Drawing on a report from consulting firm BDO, Silverman notes that biotech firms spent slightly more on R&D in 2011 than in 2010, though he adds that while large biotechs reported about 33 percent increase in revenue, smaller biotechs have not seen such large gains, reporting 12 percent decline in revenue.

"With revenues growing, it is no surprise that biotech firms are again investing substantial dollars in research and development," says BDO's Ryan Starkes in a statement. "However, broader economic challenges persist. Smaller companies are struggling to generate returns on their past investments, and continue to target innovative medicines in hopes of greater revenues down the road."

The Scan

Gap in COVAX Doses

BBC News reports that COVAX is experiencing a vaccine shortfall, as the Serum Institute of India has paused exports.

Sanofi, GSK Report Promising Results

The Wall Street Journal reports that the candidate SARS-CoV-2 vaccine from Sanofi and GlaxoSmithKline has had encouraging early results.

Influence of Luck

The New York Times examines how the US avoided variant-fueled increases in COVID-19 cases.

PLOS Papers on Retina GWAS, Hantaan Virus, COVID-19 Phenome-Wide Association Study

In PLOS this week: genome-wide association study of retinal morphology, analysis of hantaan virus found in a mouse, and more.