The UK government's recent decision to move toward enabling human trials in which mitochondrial replacement from donor DNA would be used to treat mitochondrial disease in embryos has stirred up a predictable ethical debate. Does this step effectively green-light human germline modification, a step possibly towards even more profound human genetic engineering?

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In Science this week: caution urged in use of gene drives, and more.

NIH's Sally Rockey examines the tapped and untapped potential of the NIH peer reviewer pool.

PLOS Biology has asked researchers how they envision the future of genetics and genomics.

Representative Lamar Smith brings back a provision to require the National Science Foundation to certify that each study it funds is "in the national interest."